Menopausal Hormone Therapy and Cardiovascular Diseases in Women With Vasomotor Symptoms: A Secondary Analysis of the Women’s Health Initiative Randomized Clinical Trials
JAMA Internal Medicine
•
September 15, 2025
Avoid hormone therapy after age 70
In women with hot flashes and night sweats, starting menopausal hormone therapy at age 70 or older increased artery-related heart and stroke disease, despite symptom relief in younger women. *Secondary analysis of randomized trials; Level 1b (OCEBM).
- Level of evidence
- Level 1b (OCEBM)
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