Topical therapy and vulvar malignancy risk in lichen sclerosus: a large propensity-matched study
American Journal of Obstetrics & Gynecology
•
May 01, 2026
Clobetasol may lower early vulvar cancer risk
Adults with vulvar lichen sclerosus had much higher vulvar precancer and cancer risk; early clobetasol use was linked to a small reduction in cancer at 2 years. *Retrospective propensity-matched cohort study; Level 2b (OCEBM).
- Level of evidence
- Level 2b (OCEBM)
- DocG quality score
- 6.1 / 10
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