Intranasal Treatments for Children With Sleep-Disordered Breathing: The MIST+ Randomized Clinical Trial
JAMA Pediatrics
•
January 20, 2026
Saline spray helps; steroid adds no benefit
In children with ongoing sleep-related breathing symptoms, a daily saltwater nose spray improved symptoms, and adding a steroid nose spray did not help more. *Randomized, double-blind, placebo-controlled trial; Level 1b (OCEBM).
- Level of evidence
- Level 1b (OCEBM)
- DocG quality score
- 6.5 / 10
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