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Intranasal Treatments for Children With Sleep-Disordered Breathing: The MIST+ Randomized Clinical Trial

Saline spray helps; steroid adds no benefit

In children with ongoing sleep-related breathing symptoms, a daily saltwater nose spray improved symptoms, and adding a steroid nose spray did not help more. *Randomized, double-blind, placebo-controlled trial; Level 1b (OCEBM).

Level of evidence
Level 1b (OCEBM)
DocG quality score
6.5 / 10

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