Treat-to-Target Urate-Lowering Treatment and Cardiovascular Outcomes in Patients With Gout
JAMA Internal Medicine
•
January 26, 2026
Hitting urate goal links to fewer heart events
Among adults with gout starting urate-lowering medicine, reaching a blood urate level under 6 mg/dL within 12 months was linked to fewer serious heart and stroke events over 5 years. *Emulated target trial using new-user cohort; Level 2b (OCEBM).
- Level of evidence
- Level 2b (OCEBM)
- DocG quality score
- 6.5 / 10
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