Diabetes Testing Immediately Postpartum After Gestational Diabetes Mellitus: A Randomized Controlled Trial
Doing the 2-hour sugar test before hospital discharge greatly increased postpartum diabetes testing completion and improved patient satisfaction after gestational diabetes.
*Pragmatic randomized controlled trial; Level 1b (OCEBM).
*Pragmatic randomized controlled trial; Level 1b (OCEBM).
Citation
Field C, Grobman WA, Mast D, et al. Diabetes Testing Immediately Postpartum After Gestational Diabetes Mellitus: A Randomized Controlled Trial. Obstetrics & Gynecology. 2026;147:735–744. doi:10.1097/AOG.0000000000006236
Background
Many patients with gestational diabetes do not complete recommended postpartum testing for diabetes. Testing during the delivery hospital stay may remove common barriers to follow-up testing.
Patients
104 adults with gestational diabetes at a single academic center; English or Spanish speaking; receiving prenatal and postpartum care there. Excluded: known diabetes before pregnancy or inability to tolerate the test.
Intervention
Fasting 2-hour 75-gram oral glucose tolerance test during the delivery hospitalization (before discharge).
Control
Same test scheduled as an outpatient within 12 weeks after birth (usual care).
Outcome
(Primary) Completion of the oral glucose tolerance test by 12 weeks. (Secondary) Satisfaction score using an adapted patient survey (0–36, higher is better).
Follow-up Period
Up to 12 weeks postpartum.
Results
| Outcome | Inpatient testing | Outpatient testing | Effect |
|---|---|---|---|
| Completed postpartum diabetes test (primary) | 48/52 (92.3%) | 14/52 (26.9%) | Relative risk 3.43; NNT=2 |
| Satisfaction score (0–36) | Median 35 | Median 28 | Median difference +7 points |
Analysis was intention-to-treat. Outpatient care was the current standard approach.
Limitations
Single-center, unblinded trial; many eligible patients declined participation, limiting generalizability. Satisfaction was measured at different times and in different ways between groups. Diabetes and prediabetes detection was hard to interpret because most outpatient participants never completed testing, and very early testing may over-diagnose some patients.
Funding
National Institutes of Health support; Ohio State quality improvement program.
Clinical Application
Offer inpatient oral glucose tolerance testing before discharge after gestational diabetes to improve testing completion; arrange follow-up, especially when early results suggest prediabetes or diabetes.
Journal Club
Discussion questions and an EBM quiz for this paper. How to run a journal club →
Discussion question (1)
In this pragmatic nonblinded RCT, inpatient postpartum 75-g OGTT after GDM increased diabetes testing completion by 12 weeks versus outpatient testing (92.3% vs 26.9%; RR 3.43). How valid and applicable are these results, and would they change your postpartum testing workflow?
EBM quiz (1 question)
1. In this RCT, the authors reported both a relative risk of 3.43 and an absolute risk difference of 65% for completion of postpartum OGTT with inpatient versus outpatient testing. Which statement best describes why the absolute risk difference is useful clinically?
Discussion
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