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Efficacy and Safety of an mRNA Seasonal Influenza Vaccine in Adults

Messenger RNA flu vaccine reduced flu-like illness

In adults aged 50 years or older, a messenger RNA seasonal influenza vaccine prevented more lab-confirmed influenza-like illness than a standard-dose licensed vaccine, but caused more short-term side effects. *Randomized double-blind trial; Level 1b (OCEBM).

Level of evidence
Level 1b (OCEBM)
DocG quality score
6.7 / 10

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