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One- versus Two-Sample Fecal Immunochemical Testing for Colorectal Cancer Screening: A Systematic Review and Meta-Analysis of Participation, Diagnostic Performance, and Cost-Effectiveness

One-sample testing best for screening programs

Using one stool sample keeps detection similar while reducing follow-up colonoscopies and improving participation. *Systematic review and meta-analysis of comparative studies; Level 2a (OCEBM).

Level of evidence
Level 2a (OCEBM)
DocG quality score
6.7 / 10

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