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Top Anesthesiology Research Papers
1.
7.8
Conventional vs Video-Assisted Laryngoscopy for Perioperative Endotracheal Intubations: A Randomized Clinical Trial.
Overall: A large multicenter randomized trial found clinically meaningful improvements in first-pass intubation success with readily deployable video laryngoscopy, though the primary outcome was procedural rather than a major patient outcome.
2.
7.6
Total Intravenous vs Volatile Inhalational Anesthesia for Major Noncardiac Surgery: A Randomized Clinical Trial.
Overall: A large, precise randomized trial found no clinically important recovery or safety advantage for TIVA over volatile anesthesia, despite small reductions in minor postoperative symptoms.
3.
7.5
The effect of listening to a mother's voice on emergence delirium in pediatric patients undergoing adenotonsillectomy: a prospective study.
Overall: A small randomized prospective study found a large short-term reduction in emergence delirium using a simple, low-burden intervention, but limited methodological and precision reporting reduce confidence.
4.
7.3
Integrating Nonpharmacological Options Into Perioperative Pain Care: A Cluster Randomized Clinical Trial.
Overall: A large, pragmatic US cluster-randomized trial found a modest reduction in postoperative opioid exposure without compromising patient-reported recovery, supporting scalable implementation while offering limited evidence of broader clinical benefit.
5.
7.2
Cold and Room-Temperature Platelets in Cardiac Surgery: The CHIPS Randomized Clinical Trial.
Overall: A large, well-conducted randomized trial supports substantially longer cold storage without reduced hemostatic efficacy, although no patient-level superiority was shown and increased reexploration requires attention.
6.
7.2
Sugammadex versus neostigmine for reversal of neuromuscular blockade and postoperative pulmonary complications (SNaPP): an international, randomised, controlled, phase 4 trial.
Overall: SNaPP was a strong pragmatic randomised trial showing a small reduction in postoperative pulmonary complications with sugammadex, but the result was borderline and driven mainly by atelectasis of uncertain clinical significance.
7.
7.1
Safety of routine antimicrobial prophylaxis for surgery (SAPPHIRE): a prospective multi-centre cohort study.
Overall: This large prospective cohort links additional perioperative antimicrobial doses to more adverse effects without fewer infections, but residual confounding prevents firm causal conclusions.
8.
7.1
Holding vs Continuing GLP-1/GIP Agonists Before Upper Endoscopy: The OCULUS Randomized Clinical Trial.
Overall: Holding one GLP-1 or GLP-1/GIP agonist dose substantially reduced clinically significant retained gastric contents, but the small early-terminated trial and absence of increased adverse events limit definitive practice-changing conclusions.
9.
6.8
Airway management and postoperative respiratory recovery after intravitreal injection in preterm infants.
Overall: This study reports a large association with better respiratory recovery using a practical airway option, but its retrospective single-center design and residual confounding make the findings hypothesis-generating rather than definitive.
10.
6.7
Standard Intraoperative Fluid Practices During the 2024 Intravenous Fluid Shortage.
Overall: A large US natural experiment suggests that substantial intraoperative fluid reduction may be safe and potentially beneficial, but residual confounding and absent absolute effects limit definitive practice-changing conclusions.
Score Guide:
9-10 Exceptional
7-8 Strong
5-6 Moderate
3-4 Weak
1-2 Poor
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