Top Surgery (Other) Research Papers

Overall: This well-conducted randomized trial found a clinically meaningful reduction in repeat limb procedures or major amputation without an evident one-year safety penalty, supporting potential adoption during infrainguinal angioplasty.

Overall: A strong randomized trial shows that markedly shorter systemic antibiotic therapy after local antibiotic implantation preserves clinical outcomes while substantially reducing treatment-related symptoms and burden.

Overall: A large, pragmatic US cluster-randomized trial found a modest reduction in postoperative opioid exposure without compromising patient-reported recovery, supporting scalable implementation while offering limited evidence of broader clinical benefit.

Overall: This large US observational cohort addresses a clinically important recurrence outcome and an easily actionable surgical decision, but residual confounding and the lack of absolute effect estimates limit its stand-alone practice-changing strength.

Overall: A large, well-conducted randomized trial supports substantially longer cold storage without reduced hemostatic efficacy, although no patient-level superiority was shown and increased reexploration requires attention.

Overall: This multicenter randomized US trial found markedly better local disease control with intraoperative cesium-131 tiles and similar overall adverse-event rates, but short follow-up, modified intention-to-treat exclusions, absent absolute effects, and no survival or quality-of-life results temper immediate adoption.

Overall: This randomized multicentre trial shows a substantial early organ-preservation advantage for LCCRT, but definitive functional and oncological outcomes require longer follow-up.

Overall: This rigorous trial-based US economic evaluation favors bypass surgery on cost and effectiveness, but its modest projected health advantage and remaining subgroup uncertainty temper its immediate impact.

Overall: This large prospective cohort links additional perioperative antimicrobial doses to more adverse effects without fewer infections, but residual confounding prevents firm causal conclusions.

Overall: This well-conducted US randomised trial found clinically meaningful improvements in dialysis-access function with ATEV, but more interventions, limited follow-up, and unresolved implementation issues reduce its overall impact.