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Top Hospital Medicine Research Papers

Live ranking — trailing 6 months, each paper's latest score Scores fold Hospital Medicine Relevance & Applicability into the quality dimensions; papers scored before the dynamic-specialty rubric keep their original score Showing the top 10 of 120 ranked articles — sign in free for the full ranking and per-criterion score breakdowns
1. 7.3
Effect of timing of morning blood draws on sleep quantity and quality in hospitalized patients.
Overall: Delaying routine morning blood draws produced meaningful improvements in hospitalized patients’ sleep with minimal implementation burden, but the nonrandomized design and reliance on self-report reduce certainty.
2. 6.8
Sodium Bicarbonate for In-Hospital Cardiac Arrest: A Randomized Clinical Trial.
Overall: A strong multicenter blinded trial found no meaningful benefit and more metabolic adverse effects, supporting discontinuation of routine sodium bicarbonate during in-hospital cardiac arrest.
3. 6.2
Dupilumab in chronic obstructive pulmonary disease: a pooled analysis of emergency department visits, hospital admissions, and systemic corticosteroid use.
Overall: Two large randomized trials show meaningful reductions in acute-care use among selected patients with eosinophilic COPD, although missing absolute effects, safety results, and treatment-burden details temper the clinical impact.
4. 6.2
Hospital-Onset Methicillin-Resistant Staphylococcus aureus Prevention in Acute Care Hospitals.
Overall: A large US multicenter initiative showed precise and sizable relative reductions in important infections, but its uncontrolled pre-post design, modest absolute MRSA reduction, and unreported harms limit causal confidence and practice-changing impact.
5. 6.2
Stopping or continuing chronic antihypertensive therapy during hospitalization.
Overall: This large, precise cohort reports important associations with kidney injury and mortality, but residual confounding and reverse causation substantially limit causal interpretation and immediate practice-changing value.
6. 6.2
Association between sedative prescriptions after hospital discharge and falls and other adverse events in older adults: a population-based cohort study.
Overall: This very large cohort links new post-discharge sedative use with important adverse outcomes, but residual confounding and missing effect-size details limit confidence and immediate practice-changing value.
7. 6.1
Association of Timely Antibiotics and Fluid Resuscitation With Increased Discharge to Home After Sepsis.
Overall: A large, precise US observational study links timely sepsis treatment to modestly improved home discharge, but residual confounding, unreported harms, and confirmation of existing practice limit its impact.
8. 6.1
Safety of Ultrasound-Guided Thoracentesis in Patients Receiving Direct Oral Anticoagulants: A Retrospective Cohort Study.
Overall: This clinically relevant study reports reassuring patient-important safety outcomes and an easily implemented approach, but its small, uncontrolled retrospective design leaves substantial uncertainty and limits immediate practice-changing authority.
9. 6.1
Contrast-enhanced CT-Nephrotoxic or not? A critical review of propensity-score-adjusted studies.
Overall: This clinically relevant review raises concern about a meaningful AKI risk after contrast-enhanced CT in severe chronic kidney disease, but its reliance on heterogeneous retrospective cohorts limits certainty and immediate practice-changing impact.
10. 6.0
A randomized trial of I-SLEEP: A patient education and empowerment intervention on inpatient sleep duration and medical sleep disruptions.
Overall: This relevant and practical single-center randomized trial reduced reported care disruptions but did not improve sleep duration or continuity, limiting its net benefit and immediate practice-changing impact.
Score Guide: 9-10 Exceptional 7-8 Strong 5-6 Moderate 3-4 Weak 1-2 Poor

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